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Furthermore, the observation in the study that NERD patients rapidly progressed to develop erosive esophagitis after only a very short duration of follow-up (3-6 months) may further support the conclusion that those who developed erosive esophagitis during the study period were likely healed erosive esophagitis patients that were falsely labeled as having NERD from the beginning.

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Subjects The subjects were 38 FD patients (9 male, 29 female; average age, 50 years), 25 NERD patients (16 male, 9 female; average age, 51 years) and 34 healthy volunteers (9 male, 25 female; average age, 56 years).

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